Congenital malformation syndromes with overlapping features

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Diagnostic dilemma in overlapping congenital syndromes.

Chromosomal or segmental aneusomy are an important cause of congenital malformations, emphasizing the need for cytogenetic evaluation. Many congenital malformations, especially those with multi-systemic anomalies present overlapping phenotypic features that could partly be attributed to multiple gene deregulations. Moreover, the expressivity of phenotypic features of a particular syndrome could...

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ژورنال

عنوان ژورنال: Human Pathology: Case Reports

سال: 2017

ISSN: 2214-3300

DOI: 10.1016/j.ehpc.2017.06.005